Endocrine Abstracts

Neonatal Cushing syndrome (CS) is a rather rare disease. The majority of these few cases are of ACTH dependent origin or caused by a unilateral adrenal tumour (carcinoma or adenoma), however ACTH independent bilateral hyperplasias stand for only a few percent of all cases. The management of neonatal CS depends on the underlying cause – if found in time - of the disease. In the past the survival rate of children with CS was low, new and renewed medical attempts have improv...

The authors retrospectively analyzed the efficacy of diagnostic procedures and the outcome of treatment by the analysis of data of 187 patients with primary aldosteronism (PA) examined between 1958 and 2004 at the 2nd Department of Medicine of Semmelweis University. Aldosterone-producing adenoma (APA) was detected in 135 patients, whereas idiopathic hyperaldosteronism (IHA) was found in 46 patients. Other subtypes of PA included 5 patients with unilateral primary adrenocortica...